CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28639
Family Name Protein-tyrosine kinase 2-beta inhibitor 4-N-[(1R,2R)-2-(dimethylamino)cyclopentyl]-2-N-(2,2-dioxo-1,3-dihydro-2,1-benzothiazol-5-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00486238 Functional Category Bioactive
Superfamily Tyrosine-protein kinase BTK Inhibitor CC-292 Superfamily
Class Class 1334

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 2 ligand urea deri... 3 9
Vascular endothelial growth factor receptor 2 ligand urea deri... 2 0
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486238 CHEMBL452342 Bioactive 4-N-[(1R,2R)-2-(dimethylamino)cyclopentyl]-2-N-(2,2-dioxo-1,3-dihydro-2,1-benzothiazol-5-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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