CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2864
Family Name Squalene synthase inhibitor (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(8-phenoxyoctoxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid family
No. of Seeds 8 No. of Other Members 5
Family Centroid CFAMM00338684 Functional Category Bioactive
Superfamily Squalene synthase inhibitor (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(8-phenoxyoctoxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid Superfamily
Class Class 3661

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
Acetyl-CoA carboxylase 2 Inhibitor Soraphen A Family 2 80
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Neutrophil elastase Inhibitor E-6-o-p-methoxycinnamoyl Scandos... 2 68
NF-kappa-B Inhibitor Rocaglamide Family 8 8
Squalene synthase Inhibitor Zaragozic Acid D2 Family 75 43
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Eukaryotic initiation factor 4A-I inhibitor methyl (1R,2R,3S,3... 12 1
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
4-acetylphenyl (1'S,2'R,6'R,9'R)-dispiro[cyclohexane-1,4'-[3,5... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00338690 CHEMBL265327 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6,7-dihydroxy-4-(8-phenoxyoctoxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
CFAMM00338709 CHEMBL131335 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(11-phenoxyundecanoyloxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
CFAMM00338684 CHEMBL130959 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(8-phenoxyoctoxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
CFAMM00338708 CHEMBL339319 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-7-hydroxy-4,6-bis(8-phenoxyoctoxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
CFAMM00338681 CHEMBL336939 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(11-phenoxyundecylcarbamoyloxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
CFAMM00338680 CHEMBL131147 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(11-phenoxyundecoxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
CFAMM00338677 CHEMBL262677 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6,7-dihydroxy-4-(11-phenoxyundecoxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
CFAMM00338695 CHEMBL335394 Bioactive (6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-(11-phenoxyundecoxycarbonyloxy)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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