CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28640
Family Name Aurora kinase A and Tyrosine-protein kinase SYK inhibitor AGN-PC-00CR4T family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00486239 Functional Category Bioactive
Superfamily Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta Binder Superfamily
Class Class 827

Cousin Family NamesSeedsMembers
Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Glycogen synthase kinase-3 beta Inhibitor N-(6-chloro-5-p-toly... 5 9
B1 bradykinin receptor ligand SureCN6046024 family 2 5
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 10 9
B1 bradykinin receptor ligand SureCN13770003 family 1 1
B1 bradykinin receptor ligand SureCN6045964 family 2 1
Aurora kinase A and Aurora kinase B inhibitor SureCN4059106 fa... 1 0
Neuropeptide Y receptor type 5 ligand 3-[3-[2-[[5-(4-chlorophe... 1 0


External ID

Functional Category

Molecule Name

CFAMM00486239 CHEMBL452355 Bioactive AGN-PC-00CR4T

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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