CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28662
Family Name Corticotropin-releasing factor receptor 1 ligand 2-[1-[1-[4-nitro-2-(trifluoromethyl)phenyl]-2,3-dihydropyrrolo[2,3-b]pyridin-4-yl]pyrazol-3-yl]-1,3-thiazole family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00486360 Functional Category Bioactive
Superfamily Thioredoxin glutathione reductase and Ferritin light chain Binder Superfamily
Class Class 3914

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 4
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 18
Adenosine receptor A2b and Adenosine receptor A3 ligand 3-[5-(... 4 2
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Epidermal growth factor receptor and Vascular endothelial grow... 3 1
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor Su... 2 1
Corticotropin-releasing factor receptor 1 ligand 2-[1-[1-(4-me... 5 4
Glycogen synthase kinase-3 beta inhibitor pyrazolopyrimidine d... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486360 CHEMBL457714 Bioactive 2-[1-[1-[4-nitro-2-(trifluoromethyl)phenyl]-2,3-dihydropyrrolo[2,3-b]pyridin-4-yl]pyrazol-3-yl]-1,3-thiazole
CFAMM00486362 CHEMBL458824 Bioactive 4-[4-[3-(1,3-thiazol-2-yl)pyrazol-1-yl]-2,3-dihydropyrrolo[2,3-b]pyridin-1-yl]-3-(trifluoromethyl)benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26820 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543