CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28674
Family Name Neuronal acetylcholine receptor subunit alpha-7 ligand (3R,5S)-1-methyl-5-[2-(2-methylphenyl)ethynyl]-3-(piperidin-1-ylmethyl)pyrrolidin-2-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00486397 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Ligand Org-23366 Superfamily
Class Class 620

Cousin Family NamesSeedsMembers
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 2
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Histamine H3 receptor ligand N-ethyl-3-fluoro-3-[3-fluoro-4-(p... 3 0
Kappa-type opioid receptor ligand SureCN5629426 family 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486397 CHEMBL459904 Bioactive (3R,5S)-1-methyl-5-[2-(2-methylphenyl)ethynyl]-3-(piperidin-1-ylmethyl)pyrrolidin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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