CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28678
Family Name Apoptosis regulator Bcl-2 and Bcl2-associated agonist of cell death inhibitor 4-chloro-1-[2-[(3S)-3-(hydroxymethyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]phenyl]-5-methyl-N,N-diphenylpyrazole-3-carboxamide family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00486405 Functional Category Bioactive
Superfamily Apoptosis regulator Bcl-2 and Bcl-2-like protein 1 Binder Superfamily 3
Class Class 4787

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
5-hydroxytryptamine receptor 3A ligand SureCN8035577 family 5 4
Coagulation factor X inhibitor SureCN8169809 family 12 18
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486405 CHEMBL460173 Bioactive 4-chloro-1-[2-[(3S)-3-(hydroxymethyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]phenyl]-5-methyl-N,N-diphenylpyrazole-3-carboxamide
CFAMM00486404 CHEMBL467229 Bioactive N,N-dibutyl-4-chloro-1-[2-[(3S)-3-(hydroxymethyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]phenyl]-5-methylpyrazole-3-carboxamide
CFAMM00486403 CHEMBL509788 Bioactive 4-bromo-1-[2-[(3S)-3-(hydroxymethyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]phenyl]-5-methyl-N,N-diphenylpyrazole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27520 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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