CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Mitogen-activated protein kinase 14 inhibitor 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-(3-methoxynaphthalen-1-yl)urea family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00309875 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 12 Inhibitor Birb 796 Superfamily
Class Class 851

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor Birb 796 Family 20 43
Platelet-derived growth factor receptor beta and Ephrin type-B... 9 16
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 6 6
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
Tyrosine-protein kinase Lck inhibitor AGN-PC-07R5VV family 10 0
Survival motor neuron protein inhibitor CHEMBL1496852 family 1 1


External ID

Functional Category

Molecule Name

CFAMM00309875 CHEMBL107161 Bioactive 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-(3-methoxynaphthalen-1-yl)urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



55287 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543