CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28706
Family Name C-X-C chemokine receptor type 3 ligand (1R,4S)-4-[[(3S)-4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-3-methylpiperazin-1-yl]sulfonylmethyl]-7,7-dimethylbicyclo[2.2.1]heptan-3-ol family
No. of Seeds 5 No. of Other Members 16
Family Centroid CFAMM00486498 Functional Category Bioactive
Superfamily C-X-C chemokine receptor type 3 and Cytochrome P450 1A2 Binder Superfamily
Class Class 4840

Cousin Family NamesSeedsMembers
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
C-X-C chemokine receptor type 3 and Cytochrome P450 1A2 ligand... 1 4


External ID

Functional Category

Molecule Name

CFAMM00486486 CHEMBL481198 Bioactive (1R,3S,4S)-7,7-dimethyl-4-[[(3S)-3-methyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]sulfonylmethyl]bicyclo[2.2.1]heptan-3-ol
CFAMM00486498 CHEMBL464064 Bioactive (1R,4S)-4-[[(3S)-4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-3-methylpiperazin-1-yl]sulfonylmethyl]-7,7-dimethylbicyclo[2.2.1]heptan-3-ol
CFAMM00486484 CHEMBL464244 Bioactive (2S)-4-[[(1'R,4'S)-7',7'-dimethylspiro[1,3-dioxolane-2,3'-bicyclo[2.2.1]heptane]-4'-yl]methylsulfonyl]-1-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-2-methylpiperazine
CFAMM00486497 CHEMBL464065 Bioactive (1R,3R,4S)-4-[[(3S)-4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-3-methylpiperazin-1-yl]sulfonylmethyl]-7,7-dimethylbicyclo[2.2.1]heptan-3-ol
CFAMM00486496 CHEMBL464234 Bioactive (1R,3S,4S)-4-[[(3S)-4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-3-methylpiperazin-1-yl]sulfonylmethyl]-7,7-dimethylbicyclo[2.2.1]heptan-3-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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