CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28734
Family Name Alpha-1A adrenergic receptor ligand AGN-PC-0793UT family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00486619 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor Binder Superfamily 2
Class Class 1096

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 1-... 2 9
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-i... 5 9
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Beta-1 adrenergic receptor ligand 1-[4-[2-(5-bromo-1H-imidazol... 3 8
Aromatase inhibitor AGN-PC-075MOK family 1 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 3-[2... 2 25
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Substance-P receptor and Potassium voltage-gated channel subfa... 3 6
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand 5-[(... 1 0
Alpha-2A adrenergic receptor and Alpha-1A adrenergic receptor ... 1 3
Alpha-1A adrenergic receptor and Cytochrome P450 2C19 ligand 2... 1 1
Glutaminyl-peptide cyclotransferase inhibitor thioamide deriv.... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486621 CHEMBL467915 Bioactive AGN-PC-0793VW
CFAMM00486619 CHEMBL467688 Bioactive AGN-PC-0793UT
CFAMM00486623 CHEMBL511577 Bioactive AGN-PC-0793VY

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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