CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28751
Family Name Bifunctional epoxide hydrolase 2 and Lysosomal alpha-glucosidase inhibitor STK155440 family
No. of Seeds 9 No. of Other Members 3
Family Centroid CFAMM00486681 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 and Lysosomal alpha-glucosidase Binder Superfamily
Class Class 3604

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-pent... 4 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 7 8
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 5
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-077TD5 family 1 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN10019217 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00486683 CHEMBL512659 Bioactive AGN-PC-077TDJ
CFAMM00486675 CHEMBL469360 Bioactive AGN-PC-077TCF
CFAMM00486684 CHEMBL469572 Bioactive AGN-PC-06WAB8
CFAMM00486682 CHEMBL469998 Bioactive AGN-PC-077TDK
CFAMM00486674 CHEMBL469361 Bioactive AGN-PC-077TDH
CFAMM00486681 CHEMBL469546 Bioactive STK155440
CFAMM00486687 CHEMBL469988 Bioactive AGN-PC-077TBF
CFAMM00486676 CHEMBL480496 Bioactive AGN-PC-077TC1
CFAMM00486686 CHEMBL470604 Bioactive N-[(2,4-dichlorophenyl)methyl]-1-(2,4-dimethylphenyl)sulfonylpiperidine-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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