CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28752
Family Name Tryptophan 5-hydroxylase 1 inhibitor (2S)-2-amino-3-[4-[5-[(3,4-dimethoxyphenyl)methylamino]pyrazin-2-yl]phenyl]propanoic acid family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00486690 Functional Category Bioactive
Superfamily Tryptophan 5-hydroxylase 1 and Integrin beta-5 Binder Superfamily
Class Class 2020

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Tyrosine kinase Inhibitor PKI166 Family 17 198
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 7
Lysine--tRNA ligase and Dual specificity protein kinase CLK4 i... 4 27
Dual specificity protein kinase CLK1 and Dual specificity prot... 2 14
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Cellular tumor antigen p53 and Lysosomal alpha-glucosidase inh... 1 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
Macrophage colony-stimulating factor 1 receptor and Ephrin typ... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
D(2) dopamine receptor ligand AGN-PC-07C1V6 family 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 1
Bifunctional epoxide hydrolase 2 and Arachidonate 5-lipoxygena... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486690 CHEMBL469464 Bioactive (2S)-2-amino-3-[4-[5-[(3,4-dimethoxyphenyl)methylamino]pyrazin-2-yl]phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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