CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28757
Family Name Wee1-like protein kinase inhibitor 4-(2-chlorophenyl)-9,9-dihydroxy-6-(2-hydroxyethyl)-8-(3-pyrrol-1-ylpropoxy)-8H-pyrrolo[3,4-c]carbazole-1,3-dione family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00486700 Functional Category Bioactive
Superfamily Beta-lactamase and Wee1-like protein kinase Binder Superfamily
Class Class 926

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Protein kinase C alpha type and Protein kinase C delta type in... 2 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0


External ID

Functional Category

Molecule Name

CFAMM00486700 CHEMBL469822 Bioactive 4-(2-chlorophenyl)-9,9-dihydroxy-6-(2-hydroxyethyl)-8-(3-pyrrol-1-ylpropoxy)-8H-pyrrolo[3,4-c]carbazole-1,3-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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