CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28760
Family Name Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70 inhibitor 3-[[4-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]-5-(trifluoromethyl)phenol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00486703 Functional Category Bioactive
Superfamily Cyclin-A2 and Huntingtin Binder Superfamily 3
Class Class 4752

Cousin Family NamesSeedsMembers
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor 2-(4-hydroxy... 2 15
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 5
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11
Huntingtin and Ras-related protein Rab-9A inhibitor CHEMBL1400... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486704 CHEMBL486751 Bioactive AGN-PC-077RPN
CFAMM00486703 CHEMBL470175 Bioactive 3-[[4-(1,3-thiazol-2-yl)pyrimidin-2-yl]amino]-5-(trifluoromethyl)phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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