CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2888
Family Name P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2,5-dichlorobenzamide family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00338995 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Menin Binder Superfamily
Class Class 3116

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Acetylcholinesterase Inhibitor Ambenonium Family 4 71
DNA Binder Procarbazine Family 8 358
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-5-amino-2-c... 3 4
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-amino-6-c... 1 0
Prothrombin inhibitor AGN-PC-09QJ23 family 2 5
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Cannabinoid receptor 2 ligand 1-adamantyl(1,3-dihydroisoindol-... 1 0
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-chloro-5-... 3 1
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-bromobenz... 1 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 9
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 2,6-d... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00338999 CHEMBL441479 Bioactive N-(1-adamantylmethyl)-2,3-dichlorobenzamide
CFAMM00338996 CHEMBL336619 Bioactive N-(1-adamantylmethyl)-2-chlorobenzamide
CFAMM00338995 CHEMBL131162 Bioactive N-(1-adamantylmethyl)-2,5-dichlorobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543