CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28889
Family Name Orexin receptor type 2 and Orexin receptor type 1 ligand 2-benzyl-1-(3,5-dichlorophenyl)-3-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)propane-1,3-dione family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00487088 Functional Category Bioactive
Superfamily Neuromedin-K receptor and Substance-K receptor Ligand CS-003 Superfamily
Class Class 1077

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Multidrug resistance protein Inhibitor Benzquinamide Family 1 41
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Histamine H3 receptor Ligand A-349821 Family 49 228
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
D(2) dopamine receptor Ligand Epidepride Family 31 66
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Histamine H3 receptor ligand 1-(3,4-dimethoxyphenyl)-4-(4-pent... 2 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
7-dehydrocholesterol reductase inhibitor 2-[2-(4-chlorophenyl)... 2 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00487088 CHEMBL489097 Bioactive 2-benzyl-1-(3,5-dichlorophenyl)-3-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)propane-1,3-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46031 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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