CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Nitric oxide synthase, inducible and Nuclear factor NF-kappa-B p105 subunit inhibitor N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00309881 Functional Category Bioactive
Superfamily Alpha adrenergic receptor Ligand Tolazoline Superfamily
Class Class 45

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Bethanidine Family 2 22
AMP-activated protein kinase Inhibitor Phenformin Family 5 14
Alpha adrenergic receptor Ligand Tolazoline Family 7 51
Alpha-2A adrenergic receptor Ligand Brl 44408 Family 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Nitric oxide synthase, brain Inhibitor 1-(benzhydrylamino)etha... 1 4
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 6
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 5 1
Dihydrofolate reductase inhibitor 5-[(3,5-dimethylphenyl)methy... 4 9


External ID

Functional Category

Molecule Name

CFAMM00309882 CHEMBL544788 Bioactive 1400W dihydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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