CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2892
Family Name Cellular tumor antigen p53 and Microtubule-associated protein tau inhibitor CHEMBL1409970 family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00339020 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 15
Class Class 64

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
E7820 family 9 56
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... 9 66
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Translocator protein Inhibitor 5-phenyl-6-thia-10b-aza-benzo[e... 1 2
5-hydroxytryptamine receptor 6 ligand N-methyl-1-[(1R)-6-(1H-p... 3 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-07ZA0N family 1 3
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 10 2
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
Thyrotropin receptor and Huntingtin ligand CHEMBL1333081 family 1 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 8
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 3
Platelet-activating factor receptor ligand YM-461 family 1 11
Substance-K receptor and Cytochrome P450 2D6 ligand 158848-32-... 4 4
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 12 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-quinolin-4-ylpi... 5 8
Orexin receptor type 2 and Orexin receptor type 1 ligand 2-(1-... 3 0
Platelet-activating factor receptor ligand (1-ethylindol-3-yl)... 17 13
Platelet-activating factor receptor ligand N,N-diethyl-3-[(4R)... 11 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
5-hydroxytryptamine receptor 7 ligand 6-[(2R)-2-[2-(4-methylpi... 1 0
Cannabinoid receptor 2 ligand 1-(benzenesulfonyl)-N-quinolin-3... 2 2
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00339019 CHEMBL2413373 Bioactive N-[(4-fluorophenyl)methyl]-2-[3-[(4-fluorophenyl)methylsulfonyl]indol-1-yl]-N-methylacetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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