CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28942
Family Name P2X purinoceptor 7 inhibitor 2-cyclohexyl-N'-(2-methylphenyl)acetohydrazide family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00487264 Functional Category Bioactive
Superfamily P2X purinoceptor 7 Binder Superfamily 8
Class Class 6134

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family 3 16
Myeloperoxidase Inhibitor 4-aminobenzoic Acid Hydrazide Family 1 3
Prostaglandin G/H synthase 2 inhibitor 4-chloro-N'-(4-methylph... 1 5
P2X purinoceptor 7 inhibitor N'-(2-chlorophenyl)adamantane-1-c... 2 1
P2X purinoceptor 7 inhibitor N'-(2-methylphenyl)adamantane-1-c... 3 0
P2X purinoceptor 7 inhibitor 2,2-dimethyl-3-methylidene-N'-phe... 1 2
2-(4-aminophenyl)butanedioate NP ZINC31165273 Family 4 12


External ID

Functional Category

Molecule Name

CFAMM00487258 CHEMBL496088 Bioactive 1-methyl-N'-(2-methylphenyl)cyclohexane-1-carbohydrazide
CFAMM00487264 CHEMBL509756 Bioactive 2-cyclohexyl-N'-(2-methylphenyl)acetohydrazide
CFAMM00487259 CHEMBL496085 Bioactive N'-(2-methylphenyl)cycloheptanecarbohydrazide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



42754 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543