CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28946
Family Name P2X purinoceptor 7 inhibitor N'-(2-chlorophenyl)adamantane-1-carbohydrazide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00487433 Functional Category Bioactive
Superfamily P2X purinoceptor 7 Binder Superfamily 8
Class Class 6134

Cousin Family NamesSeedsMembers
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0
P2X purinoceptor 7 inhibitor 2-cyclohexyl-N'-(2-methylphenyl)a... 3 11
P2X purinoceptor 7 inhibitor N'-(2-methylphenyl)adamantane-1-c... 3 0
P2X purinoceptor 7 inhibitor 2,2-dimethyl-3-methylidene-N'-phe... 1 2


External ID

Functional Category

Molecule Name

CFAMM00487433 CHEMBL496299 Bioactive N'-(2-chlorophenyl)adamantane-1-carbohydrazide
CFAMM00487432 CHEMBL523908 Bioactive N'-(2,3-dichlorophenyl)adamantane-1-carbohydrazide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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