CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28961
Family Name Cysteine protease and Cathepsin L1 inhibitor AGN-PC-076NDO family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00487465 Functional Category Bioactive
Superfamily Cyclin-A2 and Cathepsin L1 Binder Superfamily
Class Class 681

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Heat shock protein HSP 90-alpha Inhibitor 8-benzo[1,3]dioxol-,... 5 83
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Sodium-dependent serotonin transporter Inhibitor 4-furan-2-yl-... 2 10
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 4
Dual specificity protein kinase CLK4 and Dual specificity prot... 3 6
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 1 0
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00487465 CHEMBL497435 Bioactive AGN-PC-076NDO

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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