CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29000
Family Name Dipeptidyl peptidase 4 inhibitor (2S,4S)-4-fluoro-1-[2-[[(E)-2-methyl-4-phenylbut-3-en-2-yl]amino]acetyl]pyrrolidine-2-carbonitrile family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00487542 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 Binder Superfamily 2
Class Class 1787

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 3
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S,5S)-4-(1,3-dih... 3 14
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 5 3
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-2-[... 14 4
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 3
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
P2X purinoceptor 7 inhibitor SureCN8516206 family 5 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 3 0
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor Su... 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0
Histamine H3 receptor ligand (2S)-N-(2,3-dihydro-1H-inden-2-yl... 2 1
Dipeptidyl peptidase 4 inhibitor SureCN14523901 family 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00487542 CHEMBL508845 Bioactive (2S,4S)-4-fluoro-1-[2-[[(E)-2-methyl-4-phenylbut-3-en-2-yl]amino]acetyl]pyrrolidine-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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