CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29021
Family Name Nitric oxide synthase, inducible and Nitric oxide synthase, brain inhibitor quinolinone, 20 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00487582 Functional Category Bioactive
Superfamily Glycogen phosphorylase, muscle form Inhibitor PSN357 Superfamily
Class Class 913

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelegatran Family 8 157
Transient receptor potential cation channel subfamily V member... 16 295
Histidine decarboxylase Inhibitor Bf-derm1 Family 12 95
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
D(4) dopamine receptor Ligand SPI-376 Family 7 84
Substance-P receptor Ligand TAK-637 Family 18 63
ABC294640 family 5 75
Stress kinase p38 Inhibitor P38 Map Kinase Inhibitor Family 1 3
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Transient receptor potential cation channel subfamily V member... 6 23
Peroxisome proliferator-activated receptor gamma Ligand 2-chlo... 5 19
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Reverse transcriptase Inhibitor PT-109 Family 6 7
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Nicotinamide phosphoribosyltransferase inhibitor 4-[(7-chloro-... 6 4
B1 bradykinin receptor ligand ELN-441958 family 1 0
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 2
Nicotinamide phosphoribosyltransferase inhibitor 4-[[(7-chloro... 1 1
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 2 11
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 3 2
Seprase and Prolyl endopeptidase inhibitor [(2R)-1-[(2R)-2-[(2... 4 2
Seprase and Prolyl endopeptidase inhibitor 7-chloro-N-[2-[(2S)... 3 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[(4S)-4-(4-chlo... 4 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 3 0
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 17
Mitogen-activated protein kinase 14 inhibitor SureCN14185127 f... 2 0
Hepatocyte growth factor receptor ligand N'-(4,7-dichloro-2-ox... 2 1
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 0
C-X-C chemokine receptor type 2 ligand 6-chloro-N-(4-fluorophe... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00487582 CHEMBL512870 Bioactive quinolinone, 20

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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