CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29025
Family Name Leukotriene A-4 hydrolase and Angiotensin-converting enzyme inhibitor (2R)-3-[(4-bromophenyl)methylsulfanyl]-2-[[(2S)-2-methyl-3-sulfanylpropanoyl]amino]propanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00487588 Functional Category Bioactive
Superfamily Neprilysin Inhibitor Thiorphan Superfamily
Class Class 1538

Cousin Family NamesSeedsMembers
Neprilysin Inhibitor Thiorphan Family 41 68
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-154957 Family 2 3
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Group VII phospholipase A2 and Group 10 secretory phospholipas... 3 0
Leukotriene A-4 hydrolase and Angiotensin-converting enzyme in... 1 0


External ID

Functional Category

Molecule Name

CFAMM00487588 CHEMBL513671 Bioactive (2R)-3-[(4-bromophenyl)methylsulfanyl]-2-[[(2S)-2-methyl-3-sulfanylpropanoyl]amino]propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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