CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29029
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor AGN-PC-073RLT family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00487594 Functional Category Bioactive
Superfamily Huntingtin and Beta-lactamase Binder Superfamily 35
Class Class 1321

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Penicillin-binding protein 1B Inhibitor N-benzoyl-d-alanine Fa... 1 40
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686807 f... 7 2
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[... 10 5
Angiotensin-converting enzyme inhibitor (2S)-2-[[(2S)-1-[carbo... 2 5
Angiotensin-converting enzyme inhibitor (4R)-3-[(2S)-2-[[(1S)-... 1 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor (2S)-2... 1 3


External ID

Functional Category

Molecule Name

CFAMM00487603 CHEMBL550522 Bioactive (2R)-3-benzamido-2-[(2,3-dichlorophenyl)sulfonylamino]propanoic acid
CFAMM00487594 CHEMBL51455 Bioactive AGN-PC-073RLT

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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