CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2903
Family Name B2 bradykinin receptor ligand 4-[(E)-3-[[2-[2,4-dichloro-3-[[4-(dimethylamino)-2-methylquinolin-8-yl]oxymethyl]-N-methylanilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N,N-dimethylbenzamide;hydrochloride family
No. of Seeds 29 No. of Other Members 2
Family Centroid CFAMM00339189 Functional Category Bioactive
Superfamily B2 bradykinin receptor and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 3306

Cousin Family NamesSeedsMembers
B2 bradykinin receptor Ligand Anatibant Family 49 15
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
B2 bradykinin receptor Ligand FR-173657 Family 44 180
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
B2 bradykinin receptor ligand SureCN6578325 family 2 1
B2 bradykinin receptor ligand (E)-N-[2-[2,4-dimethoxy-N-methyl... 3 2
B2 bradykinin receptor ligand 2-(4-aminobutylcarbamoylamino)-N... 5 0
Muscarinic acetylcholine receptor M2 and Acetylcholinesterase ... 4 24
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
B2 bradykinin receptor ligand SureCN8561638 family 30 3
B2 bradykinin receptor ligand SureCN7012818 family 1 2
B2 bradykinin receptor ligand SureCN7749611 family 4 1
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
B2 bradykinin receptor ligand SureCN7977402 family 5 6
B2 bradykinin receptor ligand (E)-3-[6-(2-oxopyrrolidin-1-yl)p... 3 2
B2 bradykinin receptor ligand SureCN8516699 family 3 2
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Somatostatin receptor type 2 ligand SureCN4325675 family 3 1
Melanin-concentrating hormone receptor 1 ligand N-[3-(2-aminoq... 4 1
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 5 0
B2 bradykinin receptor ligand AGN-PC-073GJI family 2 4
B2 bradykinin receptor ligand 1-N,3-N-dimethyl-4-[methyl-[2-[[... 4 1
B2 bradykinin receptor ligand 4-[(E)-3-[[1-[2,4-dichloro-3-[(4... 3 0
B2 bradykinin receptor ligand (E)-N-[2-[N-methyl-3-[(2-methylq... 2 0
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
Neuropeptide Y receptor type 1 ligand [1-(4-chlorophenoxy)-9-[... 5 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00339189 CHEMBL541536 Bioactive 4-[(E)-3-[[2-[2,4-dichloro-3-[[4-(dimethylamino)-2-methylquinolin-8-yl]oxymethyl]-N-methylanilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N,N-dimethylbenzamide;hydrochloride
CFAMM00339182 CHEMBL541805 Bioactive 4-[(E)-3-[[2-[2,4-dichloro-N-methyl-3-[[2-methyl-4-(triazol-1-yl)quinolin-8-yl]oxymethyl]anilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N,N-dimethylbenzamide;hydrochloride
CFAMM00339188 CHEMBL439737 Bioactive SureCN7743041
CFAMM00339181 CHEMBL542096 Bioactive SureCN7748497
CFAMM00339194 CHEMBL433214 Bioactive SureCN6958626
CFAMM00339187 CHEMBL538022 Bioactive 4-[(E)-3-[[2-[2,4-dichloro-3-[(4-methoxy-2-methylquinolin-8-yl)oxymethyl]-N-methylanilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N-methylbenzamide;hydrochloride
CFAMM00339193 CHEMBL549656 Bioactive 4-[(E)-3-[[2-[2,4-dichloro-N-methyl-3-[(2-methyl-4-pyrazol-1-ylquinolin-8-yl)oxymethyl]anilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N-methylbenzamide;hydrochloride
CFAMM00339186 CHEMBL553911 Bioactive SureCN7015842
CFAMM00339192 CHEMBL544482 Bioactive 4-[(E)-3-[[2-[2,4-dichloro-3-[[4-(dimethylamino)-2-methylquinolin-8-yl]oxymethyl]-N-methylanilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N-methylbenzamide;hydrochloride
CFAMM00339185 CHEMBL552986 Bioactive SureCN7746626
CFAMM00339184 CHEMBL543070 Bioactive 4-[(E)-3-[[2-[2,4-dichloro-N-methyl-3-[(2-methyl-4-pyrazol-1-ylquinolin-8-yl)oxymethyl]anilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-N,N-dimethylbenzamide;hydrochloride
CFAMM00339190 CHEMBL262507 Bioactive SureCN6968280
CFAMM00339183 CHEMBL538274 Bioactive 4-[(E)-3-[[2-[2,4-dichloro-3-[[4-(dimethylamino)-2-methylquinolin-8-yl]oxymethyl]-N-methylanilino]-2-oxoethyl]amino]-3-oxoprop-1-enyl]-2-methoxy-N-methylbenzamide;hydrochloride
CFAMM00339196 CHEMBL553293 Bioactive SureCN7747292

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543