CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2905
Family Name Pol polyprotein inhibitor 152928-55-7 family
No. of Seeds 23 No. of Other Members 2
Family Centroid CFAMM00339214 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 21
Class Class 3367

Cousin Family NamesSeedsMembers
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Pol polyprotein inhibitor Dmp 323 family 11 44
Beta-secretase 1 and Cathepsin D inhibitor (1R,3S)-N-[(2S,3S)-... 2 25
Beta-secretase 1 inhibitor SureCN8292705 family 7 6
Beta-secretase 1 inhibitor N-[(1S,2S)-1-[(2R)-4-benzylsulfonyl... 2 0
Pol polyprotein inhibitor (4R,5R,6S,7R)-1,3,4,7-tetrabenzyl-5,... 12 29
Pol polyprotein inhibitor 183860-48-2 family 5 1
Pol polyprotein inhibitor 3-[(4R,5R,6R)-4-benzyl-3-(3-carbamoy... 3 1
Beta-secretase 1 inhibitor (2S)-2-[(3R)-3-acetamido-3-(2-methy... 3 0
Pol polyprotein inhibitor DMP-450 family 9 4
Beta-secretase 1 inhibitor 1-N-[(1R,2S)-1-[(2R,4S)-4-butoxypip... 5 1
Pol polyprotein inhibitor Cyclic Urea 64 family 12 1
Beta-secretase 1 and Cathepsin B inhibitor 3-chloro-N-[(2S)-1-... 2 0
Beta-secretase 1 and Cathepsin E inhibitor 1-N-[(1R,2S)-3-(3,5... 3 8
Pol polyprotein inhibitor 153223-22-4 family 17 10
Pol polyprotein inhibitor Cyclic Urea deriv. 9s family 4 0
Pol polyprotein inhibitor AC1LAMTC family 6 0
Pol polyprotein inhibitor [(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihy... 5 0
Pol polyprotein inhibitor AC1LAJML family 4 0
Pol polyprotein inhibitor (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihyd... 6 0
Pol polyprotein inhibitor AC1LA5V3 family 3 0
Pol polyprotein inhibitor 152929-67-4 family 1 0
Pol polyprotein inhibitor Enantiomer of AG1284 family 7 1
Pol polyprotein inhibitor AC1LADP4 family 2 0
Pol polyprotein inhibitor AC1LAH82 family 2 1
Pol polyprotein inhibitor Cyclic Urea 73 family 2 0
Pol polyprotein inhibitor Cyclic Urea deriv. 9l family 1 0
Beta-secretase 1 inhibitor SureCN8292004 family 1 0
Pol polyprotein inhibitor 3-amino-N-[(2S,3S,4R,5S)-5-[(3-amino... 2 1
Muscarinic acetylcholine receptor M3 ligand N-[[4-fluoro-3-[3-... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00339213 CHEMBL289473 Bioactive AC1LAITR
CFAMM00339226 CHEMBL86913 Bioactive 183860-43-7
CFAMM00339206 CHEMBL314008 Bioactive 167824-77-3
CFAMM00339219 CHEMBL313734 Bioactive 153183-60-9
CFAMM00339212 CHEMBL89064 Bioactive 3-[[(4R,5S,6S,7R)-3-(2-benzamidoacetyl)-4,7-dibenzyl-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]-N-(cyanomethyl)benzamide
CFAMM00339225 CHEMBL316147 Bioactive 153183-55-2
CFAMM00339205 CHEMBL304411 Bioactive AC1LAITX
CFAMM00339218 CHEMBL86441 Bioactive 183860-42-6
CFAMM00339211 CHEMBL311499 Bioactive 153183-50-7
CFAMM00339224 CHEMBL131268 Bioactive AC1LAFW2
CFAMM00339217 CHEMBL315929 Bioactive 153183-64-3
CFAMM00339210 CHEMBL304410 Bioactive AC1LAIU3
CFAMM00339223 CHEMBL81396 Bioactive 152928-65-9
CFAMM00339216 CHEMBL292631 Bioactive AC1LAIU0
CFAMM00339203 CHEMBL275024 Bioactive 183860-46-0
CFAMM00339209 CHEMBL316445 Bioactive 183860-45-9
CFAMM00339222 CHEMBL87491 Bioactive N-benzyl-3-[[(4R,5S,6S,7R)-4,7-dibenzyl-3-[[3-(benzylcarbamoyl)phenyl]methyl]-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]benzamide
CFAMM00339215 CHEMBL294331 Bioactive AC1LAITO
CFAMM00339208 CHEMBL313516 Bioactive 183860-44-8
CFAMM00339221 CHEMBL336452 Bioactive N-[(E)-but-2-enyl]-3-[[(4R,5S,6S,7R)-4,7-dibenzyl-3-[[3-[[(E)-but-2-enyl]carbamoyl]phenyl]methyl]-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl]benzamide
CFAMM00339214 CHEMBL82606 Bioactive 152928-55-7
CFAMM00339207 CHEMBL86454 Bioactive 183860-47-1
CFAMM00339220 CHEMBL291814 Bioactive AC1LAITU

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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