CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29063
Family Name Nuclear receptor ROR-gamma and Cytochrome P450 3A4 ligand NCGC00010302 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00487702 Functional Category Bioactive with Natural Product
Superfamily and Cytochrome P450 3A4 Binder Superfamily
Class Class 1144

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
SB1518 family 7 103
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Reverse transcriptase Inhibitor UK-129485 Family 23 221
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Lethal factor and Dual specificity protein kinase CLK4 inhibit... 1 3
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Dihydrofolate reductase inhibitor 2-bromo-N-[4-[4-[(2,4-diamin... 1 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Corticotropin-releasing factor receptor 1 ligand 3,6-diethyl-5... 7 8
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Transient receptor potential cation channel subfamily V member... 2 4
Mitogen-activated protein kinase kinase kinase 11 and Leucine-... 1 2
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Dihydrofolate reductase inhibitor AGN-PC-001U7R family 3 0
Dihydrofolate reductase and Dihydrofolate reductase type 1 inh... 8 1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase inhibitor 1-... 1 3
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 2
Protein kinase C theta type inhibitor SureCN3953579 family 2 1
Corticotropin-releasing factor receptor 1 ligand N-(dicyclopro... 3 35
Transient receptor potential cation channel subfamily V member... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00487702 CHEMBL521971 Bioactive NCGC00010302

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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