CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29085
Family Name Sigma non-opioid intracellular receptor 1 ligand tert-butyl 2-[2-[(4aS,10aR)-6-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-2,3,4,10a-tetrahydro-1H-phenanthren-4a-yl]ethyl-methylamino]acetate family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00487747 Functional Category Bioactive
Superfamily Sodium- and chloride-dependent glycine transporter 1 Inhibitor ALX-5407 Superfamily
Class Class 51

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 12 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00487747 CHEMBL53070 Bioactive tert-butyl 2-[2-[(4aS,10aR)-6-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-2,3,4,10a-tetrahydro-1H-phenanthren-4a-yl]ethyl-methylamino]acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27394 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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