CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29142
Family Name Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-butylpyrimidine-4,6-diamine family
No. of Seeds 16 No. of Other Members 21
Family Centroid CFAMM00487959 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Cannabinoid receptor 2 Binder Superfamily 12
Class Class 2568

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Dipeptidyl peptidase 4 inhibitor Aminomethylpyrimidine 1ck family 6 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 10
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760... 4 0
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Dihydrofolate reductase inhibitor 5-[4-[(3,4-dichlorophenyl)me... 1 0
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 2 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 3 0
Cannabinoid receptor 1 ligand 4-N-[(2S,3S)-3-(3-bromophenyl)-4... 9 0
Cannabinoid receptor 1 ligand N-[(2S,3S)-3-(3-bromophenyl)-4-(... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00487955 CHEMBL557327 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-(cyclohexylmethyl)pyrimidine-4,6-diamine
CFAMM00487947 CHEMBL557736 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-phenylpyrimidine-4,6-diamine
CFAMM00487960 CHEMBL563482 Bioactive N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-morpholin-4-ylpyrimidin-4-amine
CFAMM00487940 CHEMBL561285 Bioactive N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-butylpyrimidin-4-amine
CFAMM00487959 CHEMBL558535 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-butylpyrimidine-4,6-diamine
CFAMM00487952 CHEMBL564384 Bioactive N-[(2S)-2-(3-bromophenyl)-3-(4-chlorophenyl)propyl]-6-piperidin-1-ylpyrimidin-4-amine
CFAMM00487958 CHEMBL557058 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-cyclohexylpyrimidine-4,6-diamine
CFAMM00487938 CHEMBL549593 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-cyclopentylpyrimidine-4,6-diamine
CFAMM00487944 CHEMBL563514 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-propylpyrimidine-4,6-diamine
CFAMM00487957 CHEMBL557326 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-cycloheptylpyrimidine-4,6-diamine
CFAMM00487963 CHEMBL550672 Bioactive 4-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-N-(4-fluorophenyl)pyrimidine-4,6-diamine
CFAMM00487930 CHEMBL562798 Bioactive 6-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-4-N-pentan-3-ylpyrimidine-4,6-diamine
CFAMM00487956 CHEMBL562148 Bioactive N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-[4-(trifluoromethyl)piperidin-1-yl]pyrimidin-4-amine
CFAMM00487964 CHEMBL550941 Bioactive N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]-6-cyclohexylpyrimidin-4-amine
CFAMM00487962 CHEMBL558861 Bioactive 4-N-[(2S,3S)-2-(3-bromophenyl)-1-(4-chlorophenyl)pentan-3-yl]-6-N-cyclopentylpyrimidine-4,6-diamine
CFAMM00487942 CHEMBL561749 Bioactive 6-(azepan-1-yl)-N-[(2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl]pyrimidin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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