CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29191
Family Name D(2) dopamine receptor and D(3) dopamine receptor ligand 1-(3-chlorophenyl)-3-[2-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]ethyl]imidazolidin-2-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00488148 Functional Category Bioactive
Superfamily Retinal dehydrogenase 1 and Beta-lactamase Binder Superfamily
Class Class 3268

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Physostigmine Family 13 155
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
Substance-P receptor ligand (2S,4S)-1-N-(3-chlorophenyl)-2-N-[... 5 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 11 12
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 2 3
Melanin-concentrating hormone receptor 1 ligand 3-[4-fluoro-3-... 3 7
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 1 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8


External ID

Functional Category

Molecule Name

CFAMM00488148 CHEMBL554693 Bioactive 1-(3-chlorophenyl)-3-[2-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]ethyl]imidazolidin-2-one
CFAMM00488147 CHEMBL563926 Bioactive 1-(3-chlorophenyl)-3-[2-[2-(3-methoxyphenyl)ethyl-methylamino]ethyl]imidazolidin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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