CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2921
Family Name Pol polyprotein and Protease inhibitor Palinavir family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00339352 Functional Category Bioactive
Superfamily HIV protease Inhibitor Saquinavir Superfamily
Class Class 137

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
HIV protease Inhibitor Saquinavir Family 64 428
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
HIV-1 protease Inhibitor Atazanavir Family 16 58
CP-18770 family 6 27
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Endothelin B receptor Ligand IRL-2500 Family 34 87
Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[... 3 0
Pol polyprotein inhibitor AC1LAD48 family 19 5
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Pol polyprotein inhibitor N-[3-[[(4R,5R,6R)-4-benzyl-5-hydroxy... 1 0
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
Pol polyprotein inhibitor Carbamic acid, ((2-hydroxy-1,4-bis(p... 21 1
Pol polyprotein inhibitor AC1LAMRC family 3 0
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 1 2
C-C chemokine receptor type 1 ligand N-[(2S,3S,5R)-5-carbamoyl... 10 4
Pol polyprotein inhibitor (2S,4S,5S)-5-acetamido-6-cyclohexyl-... 3 3
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-075FXA f... 1 0
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 4 4
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[2-(1H-ind... 1 0
Caspase-1 and Caspase-8 inhibitor (4S,7S,11aS)-2-(benzenesulfo... 3 0
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7013744... 2 3
Pol polyprotein inhibitor AC1LALGZ family 2 14
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0
Pol polyprotein inhibitor 183854-15-1 family 3 0
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 8 5
Pol polyprotein inhibitor AC1LAMQU family 2 0
Pol polyprotein inhibitor (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3S)... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[4-[3-(dimethylamino)... 106 49
P2Y purinoceptor 12 inhibitor (4S)-4-[(4,6-diphenylpyridine-2-... 1 0
Pol polyprotein inhibitor 173094-24-1 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00339352 CHEMBL13134 Bioactive Palinavir

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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