CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2922
Family Name Type-1A angiotensin II receptor and Type-1B angiotensin II receptor ligand 2-[4-[(5-acetamido-2-butylbenzimidazol-1-yl)methyl]phenyl]benzoic acid family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00074943 Functional Category Bioactive
Superfamily angiotensin receptor ligand Candesartan Telmisartan Superfamily
Class Class 307

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
BIBT986 family 7 96
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing... 2 1
Eluxadoline family 4 85
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Bombesin receptor subtype-3 ligand AGN-PC-07ZAKV family 13 23
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 6 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 16 34
Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-... 2 15
Poly [ADP-ribose] polymerase 1 inhibitor SureCN6202744 family 4 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Bile acid receptor ligand 4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-d... 4 12
Microsomal triglyceride transfer protein large subunit inhibit... 7 4
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
NS5B protein inhibitor (2E)-1-cyclohexyl-2-(2-fluoro-4-oxocycl... 2 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Gastrin/cholecystokinin type B receptor ligand 3-[[5-[2-(1-ada... 9 15
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Neuropeptide Y receptor type 5 ligand SureCN4170426 family 4 13
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 7 15
Type-1 angiotensin II receptor and Type-1A angiotensin II rece... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 3
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Neuropeptide Y receptor type 5 ligand 1'-(5-CHLORO-1H-BENZIMID... 4 1
Neuropeptide Y receptor type 5 ligand AGN-PC-02WBQH family 7 1
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Melanin-concentrating hormone receptor 1 ligand SureCN3832854 ... 3 2
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RCV family 2 1
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Type-1A angiotensin II receptor ligand 2-[4-[[2-butyl-5-(tert-... 1 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 5
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-[6-[(5-ph... 1 0
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-[6-[[1-ph... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
G1/S-specific cyclin-E2 and G1/S-specific cyclin-E1 inhibitor ... 1 0
Type-1B angiotensin II receptor ligand SureCN9310003 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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