CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29251
Family Name Thromboxane-A synthase and Platelet-activating factor receptor ligand AGN-PC-00N1WP family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00488412 Functional Category Bioactive with Natural Product
Superfamily Thromboxane-A synthase and Platelet-activating factor receptor Binder Superfamily
Class Class 2472

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Smoothened homolog Inhibitor LDE225 Family 3 76
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Sodium channel protein type 10 subunit alpha and Sodium channe... 3 22
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Cannabinoid receptor 2 ligand 8-ethoxy-7-methoxy-2-oxo-N-(2-py... 2 1
Mitogen-activated protein kinase 14 inhibitor 3-fluoro-N-[4-me... 2 5
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Motilin receptor ligand SureCN2768193 family 2 1
Motilin receptor ligand SureCN2765637 family 1 1
Focal adhesion kinase 1 inhibitor 2-[[2-(2-methoxy-4-morpholin... 2 1
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Platelet-activating factor receptor ligand 5,6-dimethoxy-N,N-d... 2 3
Gastrin/cholecystokinin type B receptor and Tyrosyl-DNA phosph... 2 10
Macrophage colony-stimulating factor 1 receptor ligand 4-(2,3-... 12 7
Insulin-like growth factor 1 receptor ligand AGN-PC-050GPS family 7 0
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL4... 2 3
Histamine H3 receptor ligand AGN-PC-03Z8HB family 3 0
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 2 25
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 3
Thromboxane-A synthase and Platelet-activating factor receptor... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00488412 CHEMBL56418 Bioactive AGN-PC-00N1WP

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26858 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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