CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29283
Family Name Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibitor AGN-PC-07CRHF family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00488533 Functional Category Bioactive
Superfamily Amine oxidase [flavin-containing] B and Cathepsin B Binder Superfamily
Class Class 65

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand Ezlopitant Family 10 207
Acolbifene family 10 115
Dapoxetine family 3 40
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Fatty-acid amide hydrolase 1 Inhibitor 3-(trifluoromethyl)phen... 3 0
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 10 15
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 191
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 11
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 5 5
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9
Bifunctional epoxide hydrolase 2 inhibitor SureCN4877195 family 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-000I3M family 2 6
Putative NP ZINC04061066 Family 18 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00488534 CHEMBL585885 Bioactive AGN-PC-07CRIU
CFAMM00488533 CHEMBL567291 Bioactive AGN-PC-07CRHF

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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