CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29335
Family Name Signal transducer and activator of transcription 3 inhibitor [4-[(E)-3-[[(2S)-1-[(1R,2S,5S)-2-[[(2S)-5-amino-5-oxo-1-phenylmethoxypentan-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-methyl-1-oxopentan-2-yl]amino]-3-oxoprop-1-enyl]phenyl] dihydrogen phosphate family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00488748 Functional Category Bioactive
Superfamily Signal transducer and activator of transcription 3 Binder Superfamily 2
Class Class 5138

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Oxytocin receptor Ligand Oxytocin Family 30 182
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
Prothrombin Inhibitor Cyclotheonamide E5 Family 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Signal transducer and activator of transcription 3 inhibitor [... 7 25
Dipeptidyl peptidase 4 inhibitor ethyl 2-[[4-[[4-[(2-ethoxy-2-... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00488746 CHEMBL573443 Bioactive [4-[(E)-3-[[(2S)-1-[(1R,2S,5S)-2-[[(2R,3S)-6-amino-6-oxo-2-phenylmethoxyhexan-3-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-methyl-1-oxopentan-2-yl]amino]-3-oxoprop-1-enyl]phenyl] dihydrogen phosphate
CFAMM00488748 CHEMBL583727 Bioactive [4-[(E)-3-[[(2S)-1-[(1R,2S,5S)-2-[[(2S)-5-amino-5-oxo-1-phenylmethoxypentan-2-yl]carbamoyl]-3-azabicyclo[3.1.0]hexan-3-yl]-4-methyl-1-oxopentan-2-yl]amino]-3-oxoprop-1-enyl]phenyl] dihydrogen phosphate
CFAMM00488747 CHEMBL583728 Bioactive [4-[(E)-3-[[(2S)-4-methyl-1-oxo-1-[(1R,2S,5S)-2-(2-phenylmethoxyethylcarbamoyl)-3-azabicyclo[3.1.0]hexan-3-yl]pentan-2-yl]amino]-3-oxoprop-1-enyl]phenyl] dihydrogen phosphate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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