CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29341
Family Name Glucokinase inhibitor AGN-PC-03ZE4O family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00488775 Functional Category Bioactive
Superfamily Glucokinase and cAMP Binder Superfamily
Class Class 834

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Epidermal growth factor receptor and Mitogen-activated protein... 5 19
Receptor-type tyrosine-protein kinase FLT3 ligand 2-(6,7-dimet... 3 2
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Vascular endothelial growth factor receptor 2 ligand urea deri... 2 1
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 9
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 4 2
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 9
Deoxycytidine kinase inhibitor 2-[5-[4-[(4,6-diaminopyrimidin-... 14 11
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-1-N-(4... 3 9
Mitogen-activated protein kinase 14 inhibitor SureCN4913214 fa... 1 2
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Dihydrofolate reductase inhibitor 5-[[4-[2-[4-(4-aminophenyl)s... 1 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 7
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 0
Glucokinase inhibitor AGN-PC-03ZE5E family 1 0
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 13 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
Glucokinase inhibitor AGN-PC-00DCXR family 1 0


External ID

Functional Category

Molecule Name

CFAMM00488775 CHEMBL575918 Bioactive AGN-PC-03ZE4O
CFAMM00488772 CHEMBL573749 Bioactive AGN-PC-07COSO
CFAMM00488770 CHEMBL575904 Bioactive AGN-PC-07COSM
CFAMM00488776 CHEMBL576936 Bioactive AGN-PC-00ELZQ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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