CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29343
Family Name Histone deacetylase 1 and Histone deacetylase 2 inhibitor (2S)-N-[(5S,8R)-1,12-diamino-8-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-6-oxododecan-5-yl]-1-[2-[[2-[4-[1-[4-[1-[6-(hydroxyamino)-6-oxohexyl]triazol-4-yl]phenyl]triazol-4-yl]butanoylamino]acetyl]amino]acetyl]pyrrolidine-2-carboxamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00488780 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 20
Class Class 3270

Cousin Family NamesSeedsMembers
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Substance-P receptor Ligand GSK424887 Family 8 184
Growth hormone receptor Ligand EP-51216 Family 34 390
NS5A protein Inhibitor Bms 790052 Family 5 9
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Survival motor neuron protein and Menin inhibitor CHEMBL151109... 1 11
Proteinase-activated receptor 1 and Prothrombin ligand (2S)-N-... 3 23
KiSS-1 receptor ligand SureCN5132924 family 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00488781 CHEMBL582926 Bioactive (2S)-N-[(5S,8R)-1,12-diamino-8-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-6-oxododecan-5-yl]-1-[2-[[2-[4-[1-[4-[1-[7-(hydroxyamino)-7-oxoheptyl]triazol-4-yl]phenyl]triazol-4-yl]butanoylamino]acetyl]amino]acetyl]pyrrolidine-2-carboxamide
CFAMM00488780 CHEMBL573899 Bioactive (2S)-N-[(5S,8R)-1,12-diamino-8-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-6-oxododecan-5-yl]-1-[2-[[2-[4-[1-[4-[1-[6-(hydroxyamino)-6-oxohexyl]triazol-4-yl]phenyl]triazol-4-yl]butanoylamino]acetyl]amino]acetyl]pyrrolidine-2-carboxamide
CFAMM00488779 CHEMBL573900 Bioactive (2S)-N-[(5S,8R)-1,12-diamino-8-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[2-[(2-amino-2-oxoethyl)amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]carbamoyl]-6-oxododecan-5-yl]-1-[2-[[2-[4-[1-[4-[1-[8-(hydroxyamino)-8-oxooctyl]triazol-4-yl]phenyl]triazol-4-yl]butanoylamino]acetyl]amino]acetyl]pyrrolidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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