CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29359
Family Name Bifunctional dihydrofolate reductase-thymidylate synthase and Dihydrofolate reductase inhibitor AC1LAJK9 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00488821 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Bifunctional dihydrofolate reductase-thymidylate synthase Binder Superfamily 4
Class Class 1144

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Tyrosine-protein kinase SYK Inhibitor R788 Family 3 7
Glycogen synthase kinase-3 alpha and Casein kinase II subunit ... 1 16
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
ALK tyrosine kinase receptor and Insulin-like growth factor 1 ... 1 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00488821 CHEMBL57682 Bioactive AC1LAJK9

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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