CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29477
Family Name Glutamate carboxypeptidase 2 inhibitor 2-(4-hydroxy-3-methoxyphenyl)-2-[[(2S)-4-methyl-1-oxo-1-propan-2-yloxypentan-2-yl]carbamoylamino]acetic acid family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00489183 Functional Category Bioactive with Natural Product
Superfamily Tubulin beta chain Inhibitor 6-ile-ustiloxin Superfamily
Class Class 2351

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Zucapsacin family 7 177
Vasopeptidase Inhibitor Fasidotril Family 3 7
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Tubulin beta chain Inhibitor 6-ile-ustiloxin Family 4 3
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Prothrombin inhibitor (2S)-N-[(4-aminocyclohexyl)methyl]-1-[2-... 1 0
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Pol polyprotein inhibitor AC1LA3AI family 5 9
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-07... 2 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[(4... 1 0


External ID

Functional Category

Molecule Name

CFAMM00489183 CHEMBL596208 Bioactive 2-(4-hydroxy-3-methoxyphenyl)-2-[[(2S)-4-methyl-1-oxo-1-propan-2-yloxypentan-2-yl]carbamoylamino]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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