CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29480
Family Name D(2) dopamine receptor and D(4) dopamine receptor ligand 3-[1-[(1-methylbenzimidazol-2-yl)methyl]piperidin-4-yl]-1,2-benzothiazole family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00489204 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor Binder Superfamily
Class Class 2000

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Emedastine Family 5 115
Histamine H1 receptor Ligand Mizolastine Family 14 603
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
HCV NS4B protein Inhibitor Clemizole Family 2 43
Tryptase Inhibitor Babim Family 12 90
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... 4 4
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
Cannabinoid receptor 2 ligand 2-tert-butyl-5-ethylsulfonyl-1-(... 28 32
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Type-1 angiotensin II receptor ligand SureCN7390271 family 2 1
Type-1 angiotensin II receptor ligand AGN-PC-04X8EF family 1 1
Gonadotropin-releasing hormone receptor ligand 4-[[4-[2-(4-ter... 3 3
Nuclear receptor subfamily 1 group I member 2 ligand AGN-PC-07... 2 13
Nociceptin receptor and Mu-type opioid receptor ligand 2-(3-ch... 2 0
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00489204 CHEMBL596527 Bioactive 3-[1-[(1-methylbenzimidazol-2-yl)methyl]piperidin-4-yl]-1,2-benzothiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26384 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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