CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29485
Family Name Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor N-[5-(2,2-dimethylpropanoyl)-6,6-dimethyl-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]pyridine-3-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00489216 Functional Category Bioactive
Superfamily Cyclin-A2 and Cyclin-dependent kinase 2 Binder Superfamily 5
Class Class 1185

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Cell division cycle 7-related protein kinase and Casein kinase... 2 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00489217 CHEMBL606412 Bioactive AGN-PC-07R89T
CFAMM00489216 CHEMBL597391 Bioactive N-[5-(2,2-dimethylpropanoyl)-6,6-dimethyl-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]pyridine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26224 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543