CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29586
Family Name Squalene--hopene cyclase and Lanosterol synthase inhibitor R17 family
No. of Seeds 1 No. of Other Members 22
Family Centroid CFAMM00489585 Functional Category Bioactive with Natural Product
Superfamily Squalene--hopene cyclase and Lanosterol synthase inhibitor R17 Superfamily
Class Class 4333

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
DNA Binder Methoxsalen Family 10 1638
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Ipriflavone family 62 2480
DNA-dependent protein kinase catalytic subunit Inhibitor 7-pro... 5 49
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Amine oxidase [flavin-containing] B Inhibitor 8-bromo-6-methyl... 5 44
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-b... 6 21
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 11
1-benzofuran-3-one NP ZINC09486173 Family 33 0
NP Agn-pc-054n5h Family 5 0
Putative NP ZINC20357755 Family 11 0
2-(trifluoromethyl)chromen-4-one NP ZINC02418160 Family 7 0
6-hydroxy-7-(morpholin-4-ylmethyl)-1-benzofuran-3-one NP ZINC2... 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00489585 CHEMBL65553 Bioactive R17

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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