CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29605
Family Name Glycogen synthase kinase-3 beta inhibitor pyrazolopyrimidine derivative 28 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00489630 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and Prelamin-A/C Binder Superfamily 13
Class Class 3366

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Prothrombin and Histone-lysine N-methyltransferase 2A inhibito... 1 7
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 18
Histamine H3 receptor ligand 2-(3-methyl-[1,2,4]triazolo[4,3-a... 1 0
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 1 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 3 0
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor Su... 2 1
Corticotropin-releasing factor receptor 1 ligand 2-[1-[1-[4-ni... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00489630 CHEMBL68397 Bioactive pyrazolopyrimidine derivative 28

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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