CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2965
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-PC-075KPC family
No. of Seeds 2 No. of Other Members 17
Family Centroid CFAMM00340066 Functional Category Bioactive
Superfamily Beta-lactamase and Nuclear receptor ROR-gamma Binder Superfamily 6
Class Class 656

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Sodium-dependent noradrenaline transporter Inhibitor Neri Iv F... 6 58
Glucokinase Inhibitor GKA1 Family 2 67
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
P2X purinoceptor 7 Inhibitor A-740003 Family 2 6
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Ferritin light chain and Ras-related protein Rab-9A inhibitor ... 1 11
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Renin inhibitor SureCN7300793 family 2 5
Platelet-activating factor receptor ligand [(2R,4R)-4-(octadec... 3 2
C-C chemokine receptor type 8 and Potassium voltage-gated chan... 1 1


External ID

Functional Category

Molecule Name

CFAMM00340070 CHEMBL134237 Bioactive AGN-PC-075KOD
CFAMM00340066 CHEMBL131565 Bioactive AGN-PC-075KPC

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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