CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Adenosine receptor A1 ligand 4-[5-(8-cyclopentyl-2,6-dioxo-1-propyl-7H-purin-3-yl)pentanoyl]benzenesulfonyl fluoride family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00309936 Functional Category Bioactive
Superfamily Adenosine receptor A1 and cAMP-specific 3',5'-cyclic phosphodiesterase 4A Binder Superfamily
Class Class 1165

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Prelamin-A/C inhibitor CHEMBL1503535 family 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Adenosine receptor A1 ligand 3-(4-Aminophenethyl)-8-(3-noradam... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand FSCPX ... 3 0


External ID

Functional Category

Molecule Name

CFAMM00309936 CHEMBL107499 Bioactive 4-[5-(8-cyclopentyl-2,6-dioxo-1-propyl-7H-purin-3-yl)pentanoyl]benzenesulfonyl fluoride
CFAMM00309935 CHEMBL107646 Bioactive 4-[5-[8-(3-bicyclo[2.2.1]heptanyl)-2,6-dioxo-1-propyl-7H-purin-3-yl]pentanoyl]benzenesulfonyl fluoride
CFAMM00309933 CHEMBL108552 Bioactive 4-[5-(8-cyclohexyl-2,6-dioxo-1-propyl-7H-purin-3-yl)pentanoyl]benzenesulfonyl fluoride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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