CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29712
Family Name Sigma non-opioid intracellular receptor 1 and Sodium-dependent dopamine transporter ligand N-[3-[(3R,5R)-4-[2-(3,4-dichlorophenyl)ethyl]-3,5-dimethylpiperazin-1-yl]propyl]-N-phenylaniline family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00489889 Functional Category Bioactive
Superfamily D(4) dopamine receptor and Alpha-1B adrenergic receptor Binder Superfamily
Class Class 3297

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Serotonin re-uptake inhibitor Dibenzazepine Clomipramine Family 2 23
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichloropheny... 2 10
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 34
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 1 2
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 6
5-hydroxytryptamine receptor 2A ligand AGN-PC-075LXD family 4 4
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 0
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
C-C chemokine receptor type 2 ligand (E)-3-(3,4-dichlorophenyl... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00489890 CHEMBL86830 Bioactive N-[3-[(3R,5R)-4-[2-(3,4-dichlorophenyl)ethyl]-3,5-dimethylpiperazin-1-yl]propyl]-4-fluoro-N-(4-fluorophenyl)aniline
CFAMM00489889 CHEMBL84971 Bioactive N-[3-[(3R,5R)-4-[2-(3,4-dichlorophenyl)ethyl]-3,5-dimethylpiperazin-1-yl]propyl]-N-phenylaniline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44593 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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