CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29729
Family Name Calpain-1 catalytic subunit and Cathepsin B inhibitor [(3R,5S)-1-(benzenesulfonyl)-5-[[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-3-yl] benzenesulfonate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00489923 Functional Category Bioactive
Superfamily Beta-lactamase and Cathepsin B Binder Superfamily
Class Class 3217

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Calpain Inhibitor SJA-6017 Family 2 12
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Calpain-1 catalytic subunit and Cathepsin B inhibitor (2R)-N-[... 2 2
Calpain-1 catalytic subunit and Cathepsin B inhibitor (4S)-3-(... 1 0


External ID

Functional Category

Molecule Name

CFAMM00489923 CHEMBL87146 Bioactive [(3R,5S)-1-(benzenesulfonyl)-5-[[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-3-yl] benzenesulfonate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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