CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29740
Family Name Histamine H3 receptor ligand (NE)-N-[2-[2-(dimethylamino)ethoxy]fluoren-9-ylidene]hydroxylamine family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00489958 Functional Category Bioactive
Superfamily Oestrogen receptor Ligand Lasofoxifene Superfamily
Class Class 142

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Androgen receptor Ligand 4-(m-tolyloxy)-2-(trifluoromethyl)ben... 7 65
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
Sodium-dependent serotonin transporter and Alpha-2A adrenergic... 2 2
Luciferin 4-monooxygenase inhibitor (5R)-5-benzyl-3-(4-methoxy... 5 9
Peroxisome proliferator-activated receptor gamma ligand 2-etho... 5 11
Peroxisome proliferator-activated receptor gamma ligand 2-etho... 6 2
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9


External ID

Functional Category

Molecule Name

CFAMM00489956 CHEMBL89224 Bioactive (NE)-N-[2-(2-pyrrolidin-1-ylethoxy)fluoren-9-ylidene]hydroxylamine
CFAMM00489955 CHEMBL89869 Bioactive (NE)-N-[2-[3-(dimethylamino)propoxy]fluoren-9-ylidene]hydroxylamine
CFAMM00489958 CHEMBL88748 Bioactive (NE)-N-[2-[2-(dimethylamino)ethoxy]fluoren-9-ylidene]hydroxylamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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