CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29823
Family Name Caspase-3 and Caspase-7 inhibitor (2S)-N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-4-methyl-2-[(2-quinolin-4-yloxyacetyl)amino]pentanamide family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00490189 Functional Category Bioactive with Natural Product
Superfamily Caspase-3 and Caspase-7 Binder Superfamily 4
Class Class 2449

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 2 15
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 8 3
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 2 11
Substance-P receptor ligand SureCN2139814 family 7 7
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Substance-P receptor ligand AGN-PC-00FIT5 family 3 11
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00490188 CHEMBL318295 Bioactive (2S)-N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-4-methyl-2-[(2-quinolin-5-yloxyacetyl)amino]pentanamide
CFAMM00490187 CHEMBL101341 Bioactive (2S)-N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-4-methyl-2-[(2-quinolin-8-yloxyacetyl)amino]pentanamide
CFAMM00490186 CHEMBL101684 Bioactive (2S)-N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-2-[(2-isoquinolin-5-yloxyacetyl)amino]-4-methylpentanamide
CFAMM00490189 CHEMBL100927 Bioactive (2S)-N-[(3S)-2-hydroxy-5-oxooxolan-3-yl]-4-methyl-2-[(2-quinolin-4-yloxyacetyl)amino]pentanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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