CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM29933
Family Name Estradiol 17-beta-dehydrogenase 1 inhibitor SureCN4589665 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00490441 Functional Category Bioactive with Natural Product
Superfamily Integrase and GABA theta subunit Binder Superfamily
Class Class 2073

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Oestrogen receptor Ligand Mestranol Family 2 29
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Translocator protein Inhibitor Dextofisopam Family 3 250
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Carbonic anhydrase 2 and Steryl-sulfatase Inhibitor 2-methoxye... 2 7
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Integrase inhibitor 4-[(10S,13R)-3,7,12-tris[[(E)-3-(3,4-dihyd... 1 0
Steryl-sulfatase inhibitor [(8R,9S,13S,14S)-13-methyl-17-oxo-7... 1 9
Aromatase inhibitor AGN-PC-075LLF family 1 0
Prenol Lipids Metabolite 7-Methylrosmanol Family 4 11
Steroids and Steroid Derivatives Metabolite Oryzanol C Family 5 2
Phenols and Derivatives Metabolite 6-Gingesulfonic acid Family 1 2
Prenol Lipids Metabolite Rosmadial Family 1 0
Acenes Metabolite Musanolone D Family 2 1


External ID

Functional Category

Molecule Name

CFAMM00490441 CHEMBL1080307 Bioactive SureCN4589665
CFAMM00490435 CHEMBL1081172 Bioactive CHEMBL1081172

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



112433 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543